ATP is stored in lamellar bodies to activate vesicular P2X(4) in an autocrine fashion upon exocytosis

Vesicular P2X(4) receptors are known to facilitate secretion and activation of pulmonary surfactant in the alveoli of the lungs. P2X(4) receptors are expressed in the membrane of lamellar bodies (LBs), large secretory lysosomes that store lung surfactant in alveolar type II epithelial cells, and bec...

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Detalles Bibliográficos
Autores principales: Fois, Giorgio, Winkelmann, Veronika Eva, Bareis, Lara, Staudenmaier, Laura, Hecht, Elena, Ziller, Charlotte, Ehinger, Konstantin, Schymeinsky, Jürgen, Kranz, Christine, Frick, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806682/
https://www.ncbi.nlm.nih.gov/pubmed/29282210
http://dx.doi.org/10.1085/jgp.201711870

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