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The Preciseness in Diagnosing Thyroid Malignant Nodules Using Shear-Wave Elastography

Our study aimed to identify more accurate results about the diagnostic role of shear-wave elastography (SWE) for thyroid malignant nodules through a meta-analysis. Potential articles were searched in PubMed, Embase, and the Cochrane Library databases. Overall sensitivity and specificity with 95% con...

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Autores principales: Chang, Na, Zhang, Xianchao, Wan, Wenjing, Zhang, Chengqi, Zhang, Xianqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806774/
https://www.ncbi.nlm.nih.gov/pubmed/29391387
http://dx.doi.org/10.12659/MSM.904703
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author Chang, Na
Zhang, Xianchao
Wan, Wenjing
Zhang, Chengqi
Zhang, Xianqi
author_facet Chang, Na
Zhang, Xianchao
Wan, Wenjing
Zhang, Chengqi
Zhang, Xianqi
author_sort Chang, Na
collection PubMed
description Our study aimed to identify more accurate results about the diagnostic role of shear-wave elastography (SWE) for thyroid malignant nodules through a meta-analysis. Potential articles were searched in PubMed, Embase, and the Cochrane Library databases. Overall sensitivity and specificity with 95% confidence intervals (CIs) was used to represent the diagnostic accuracy of SWE. Summary receiver operating characteristic (ROC) curve was constructed to illustrate the results. In addition, χ(2) and I(2) tests were performed to assess heterogeneity. A value of p≤0.05 indicated significant heterogeneity. All the analysis was conducted in Meta-DiSc version 1.4 software. Twenty studies were included in the analysis. There were a total of 2,907 patients and 3,397 thyroid nodules included in the meta-analysis. Overall sensitivity and specificity were 0.68 (95% CI: 0.66–0.70) and 0.85 (95% CI: 0.84–0.87), respectively. The results showed the area under curve (AUC) was 0.9041, suggesting high accuracy of SWE for differentiating benign and malignant thyroid nodules. SWE showed high accuracy in identifying thyroid malignant nodules, suggesting it could serve as a diagnostic biomarker in thyroid nodules.
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spelling pubmed-58067742018-02-13 The Preciseness in Diagnosing Thyroid Malignant Nodules Using Shear-Wave Elastography Chang, Na Zhang, Xianchao Wan, Wenjing Zhang, Chengqi Zhang, Xianqi Med Sci Monit Hypothesis Our study aimed to identify more accurate results about the diagnostic role of shear-wave elastography (SWE) for thyroid malignant nodules through a meta-analysis. Potential articles were searched in PubMed, Embase, and the Cochrane Library databases. Overall sensitivity and specificity with 95% confidence intervals (CIs) was used to represent the diagnostic accuracy of SWE. Summary receiver operating characteristic (ROC) curve was constructed to illustrate the results. In addition, χ(2) and I(2) tests were performed to assess heterogeneity. A value of p≤0.05 indicated significant heterogeneity. All the analysis was conducted in Meta-DiSc version 1.4 software. Twenty studies were included in the analysis. There were a total of 2,907 patients and 3,397 thyroid nodules included in the meta-analysis. Overall sensitivity and specificity were 0.68 (95% CI: 0.66–0.70) and 0.85 (95% CI: 0.84–0.87), respectively. The results showed the area under curve (AUC) was 0.9041, suggesting high accuracy of SWE for differentiating benign and malignant thyroid nodules. SWE showed high accuracy in identifying thyroid malignant nodules, suggesting it could serve as a diagnostic biomarker in thyroid nodules. International Scientific Literature, Inc. 2018-02-02 /pmc/articles/PMC5806774/ /pubmed/29391387 http://dx.doi.org/10.12659/MSM.904703 Text en © Med Sci Monit, 2018 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Hypothesis
Chang, Na
Zhang, Xianchao
Wan, Wenjing
Zhang, Chengqi
Zhang, Xianqi
The Preciseness in Diagnosing Thyroid Malignant Nodules Using Shear-Wave Elastography
title The Preciseness in Diagnosing Thyroid Malignant Nodules Using Shear-Wave Elastography
title_full The Preciseness in Diagnosing Thyroid Malignant Nodules Using Shear-Wave Elastography
title_fullStr The Preciseness in Diagnosing Thyroid Malignant Nodules Using Shear-Wave Elastography
title_full_unstemmed The Preciseness in Diagnosing Thyroid Malignant Nodules Using Shear-Wave Elastography
title_short The Preciseness in Diagnosing Thyroid Malignant Nodules Using Shear-Wave Elastography
title_sort preciseness in diagnosing thyroid malignant nodules using shear-wave elastography
topic Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806774/
https://www.ncbi.nlm.nih.gov/pubmed/29391387
http://dx.doi.org/10.12659/MSM.904703
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