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Intragenic DNA methylation of PITX1 and the adjacent long non-coding RNA C5orf66-AS1 are prognostic biomarkers in patients with head and neck squamous cell carcinomas

BACKGROUND: Patients with squamous cell cancer of the head and neck region (HNSCC) are at risk for disease recurrence and metastases, even after initial successful therapy. A tissue-based biomarker could be beneficial to guide treatment as well as post-treatment surveillance. Gene methylation status...

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Detalles Bibliográficos
Autores principales:	Sailer, Verena, Charpentier, Arthur, Dietrich, Joern, Vogt, Timo J., Franzen, Alina, Bootz, Friedrich, Dietrich, Dimo, Schroeck, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806891/ https://www.ncbi.nlm.nih.gov/pubmed/29425237 http://dx.doi.org/10.1371/journal.pone.0192742

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