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A new mechanism of interferon’s antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7
The interferon (IFN) system represents the first line of defense against a wide range of viruses. Virus infection rapidly triggers the transcriptional induction of IFN-β and IFN Stimulated Genes (ISGs), whose protein products act as viral restriction factors by interfering with specific stages of vi...
Autores principales: | Subramanian, Gayatri, Kuzmanovic, Teodora, Zhang, Ying, Peter, Cara Beate, Veleeparambil, Manoj, Chakravarti, Ritu, Sen, Ganes C., Chattopadhyay, Saurabh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806901/ https://www.ncbi.nlm.nih.gov/pubmed/29381763 http://dx.doi.org/10.1371/journal.ppat.1006877 |
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