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The KCa3.1 blocker TRAM34 reverses renal damage in a mouse model of established diabetic nephropathy

Despite optimal control of hyperglycaemia, hypertension, and dyslipidaemia, the number of patients with diabetic nephropathy (DN) continues to grow. Strategies to target various signaling pathways to prevent DN have been intensively investigated in animal models and many have been proved to be promi...

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Detalles Bibliográficos
Autores principales: Huang, Chunling, Zhang, Ling, Shi, Ying, Yi, Hao, Zhao, Yongli, Chen, Jason, Pollock, Carol A., Chen, Xin-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806905/
https://www.ncbi.nlm.nih.gov/pubmed/29425253
http://dx.doi.org/10.1371/journal.pone.0192800