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Dentin Erosion: Method Validation and Efficacy of Fluoride Protection

The aging population experiences more gingival recession and root exposure which increases the opportunity for dentin erosion. This study tested the use of transverse microradiography (TMR) methods to assess dentin erosion and the interaction between fluoride and citric acid on the amount of erosion...

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Autores principales: Carey, Clifton M., Brown, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806968/
https://www.ncbi.nlm.nih.gov/pubmed/29563433
http://dx.doi.org/10.3390/dj5040027
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author Carey, Clifton M.
Brown, William
author_facet Carey, Clifton M.
Brown, William
author_sort Carey, Clifton M.
collection PubMed
description The aging population experiences more gingival recession and root exposure which increases the opportunity for dentin erosion. This study tested the use of transverse microradiography (TMR) methods to assess dentin erosion and the interaction between fluoride and citric acid on the amount of erosion in the dentin samples. In a 4 × 3 interaction experimental design, four fluoride concentrations (0.00, 25.0, 50.0, and 100.0 mg/L) and three citric acid concentrations (0.0, 0.25, and 1.00%) were combined to form 12 experimental solutions. Forty-eight dentin samples were placed in the experimental solutions for 1 and 4 h and the amount of surface lost was determined by TMR methods. The resolution of the TMR method was 0.9 μm per pixel with a 0.1% and a 5% confidence interval of ±4.2 μm. Dentin erosion increased with the concentration of citric acid and time, the erosion decreased when concentration of fluoride was increased. Effects due to fluoride and citric acid concentrations individually, and their interaction on the amount of erosion observed was statistically significant (p < 0.0001). This study found that TMR methods are appropriate and that 25.0 mg/L was the optimal fluoride concentration to protect dentin from a 1.00% citric acid challenge.
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spelling pubmed-58069682018-03-16 Dentin Erosion: Method Validation and Efficacy of Fluoride Protection Carey, Clifton M. Brown, William Dent J (Basel) Article The aging population experiences more gingival recession and root exposure which increases the opportunity for dentin erosion. This study tested the use of transverse microradiography (TMR) methods to assess dentin erosion and the interaction between fluoride and citric acid on the amount of erosion in the dentin samples. In a 4 × 3 interaction experimental design, four fluoride concentrations (0.00, 25.0, 50.0, and 100.0 mg/L) and three citric acid concentrations (0.0, 0.25, and 1.00%) were combined to form 12 experimental solutions. Forty-eight dentin samples were placed in the experimental solutions for 1 and 4 h and the amount of surface lost was determined by TMR methods. The resolution of the TMR method was 0.9 μm per pixel with a 0.1% and a 5% confidence interval of ±4.2 μm. Dentin erosion increased with the concentration of citric acid and time, the erosion decreased when concentration of fluoride was increased. Effects due to fluoride and citric acid concentrations individually, and their interaction on the amount of erosion observed was statistically significant (p < 0.0001). This study found that TMR methods are appropriate and that 25.0 mg/L was the optimal fluoride concentration to protect dentin from a 1.00% citric acid challenge. MDPI 2017-10-06 /pmc/articles/PMC5806968/ /pubmed/29563433 http://dx.doi.org/10.3390/dj5040027 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Carey, Clifton M.
Brown, William
Dentin Erosion: Method Validation and Efficacy of Fluoride Protection
title Dentin Erosion: Method Validation and Efficacy of Fluoride Protection
title_full Dentin Erosion: Method Validation and Efficacy of Fluoride Protection
title_fullStr Dentin Erosion: Method Validation and Efficacy of Fluoride Protection
title_full_unstemmed Dentin Erosion: Method Validation and Efficacy of Fluoride Protection
title_short Dentin Erosion: Method Validation and Efficacy of Fluoride Protection
title_sort dentin erosion: method validation and efficacy of fluoride protection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806968/
https://www.ncbi.nlm.nih.gov/pubmed/29563433
http://dx.doi.org/10.3390/dj5040027
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