YTH-RNA-binding protein prevents deleterious expression of meiotic proteins by tethering their mRNAs to nuclear foci

Accurate and extensive regulation of meiotic gene expression is crucial to distinguish germ cells from somatic cells. In the fission yeast Schizosaccharomyces pombe, a YTH family RNA-binding protein, Mmi1, directs the nuclear exosome-mediated elimination of meiotic transcripts during vegetative prol...

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Detalles Bibliográficos
Autores principales: Shichino, Yuichi, Otsubo, Yoko, Kimori, Yoshitaka, Yamamoto, Masayuki, Yamashita, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807050/
https://www.ncbi.nlm.nih.gov/pubmed/29424342
http://dx.doi.org/10.7554/eLife.32155

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