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Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions
Mechanical properties are cues for many biological processes in health or disease. In the heart, changes to the extracellular matrix composition and cross-linking result in stiffening of the cellular microenvironment during development. Moreover, myocardial infarction and cardiomyopathies lead to fi...
Autores principales: | Pandey, Pragati, Hawkes, William, Hu, Junquiang, Megone, William Valentine, Gautrot, Julien, Anilkumar, Narayana, Zhang, Min, Hirvonen, Liisa, Cox, Susan, Ehler, Elisabeth, Hone, James, Sheetz, Michael, Iskratsch, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807060/ https://www.ncbi.nlm.nih.gov/pubmed/29396114 http://dx.doi.org/10.1016/j.devcel.2017.12.024 |
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