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Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline

Supplementation of spermidine, an autophagy-inducing agent, has been shown to protect against neurodegeneration and cognitive decline in aged animal models. The present translational study aimed to determine safety and tolerability of a wheat germ extract containing enhanced spermidine concentration...

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Detalles Bibliográficos
Autores principales:	Schwarz, Claudia, Stekovic, Slaven, Wirth, Miranka, Benson, Gloria, Royer, Philipp, Sigrist, Stephan J, Pieber, Thomas, Dammbrueck, Christopher, Magnes, Christoph, Eisenberg, Tobias, Pendl, Tobias, Bohlken, Jens, Köbe, Theresa, Madeo, Frank, Flöel, Agnes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807086/ https://www.ncbi.nlm.nih.gov/pubmed/29315079 http://dx.doi.org/10.18632/aging.101354

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