Rifampicin-Induced Fever in a Patient with Brucellosis: A Case Report

We present a 35-year-old female patient who was started on rifampicin (900 mg orally once daily) and trimethoprim/sulfamethoxazole (TMP/SMX) (160/800 mg orally twice daily) after being diagnosed with brucellosis. Following defervescence and improvement in her general condition, fever recurred on the...

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Detalles Bibliográficos
Autores principales: Yilmaz, Mesut, Yasar, Canan, Aydin, Selda, Derin, Okan, Ceylan, Bahadir, Mert, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807255/
https://www.ncbi.nlm.nih.gov/pubmed/29427095
http://dx.doi.org/10.1007/s40800-018-0074-3
Descripción
Sumario:We present a 35-year-old female patient who was started on rifampicin (900 mg orally once daily) and trimethoprim/sulfamethoxazole (TMP/SMX) (160/800 mg orally twice daily) after being diagnosed with brucellosis. Following defervescence and improvement in her general condition, fever recurred on the 12th day of treatment. A re-challenge drug test lead to causality assessment and treatment was switched to a combination of streptomycin (1 g intramuscularly) for 10 days and TMP/SMX (160/800 mg orally twice daily) for 4 weeks. Our patient is doing well after 12 months of follow-up.

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