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Rifampicin-Induced Fever in a Patient with Brucellosis: A Case Report

We present a 35-year-old female patient who was started on rifampicin (900 mg orally once daily) and trimethoprim/sulfamethoxazole (TMP/SMX) (160/800 mg orally twice daily) after being diagnosed with brucellosis. Following defervescence and improvement in her general condition, fever recurred on the...

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Autores principales: Yilmaz, Mesut, Yasar, Canan, Aydin, Selda, Derin, Okan, Ceylan, Bahadir, Mert, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807255/
https://www.ncbi.nlm.nih.gov/pubmed/29427095
http://dx.doi.org/10.1007/s40800-018-0074-3
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author Yilmaz, Mesut
Yasar, Canan
Aydin, Selda
Derin, Okan
Ceylan, Bahadir
Mert, Ali
author_facet Yilmaz, Mesut
Yasar, Canan
Aydin, Selda
Derin, Okan
Ceylan, Bahadir
Mert, Ali
author_sort Yilmaz, Mesut
collection PubMed
description We present a 35-year-old female patient who was started on rifampicin (900 mg orally once daily) and trimethoprim/sulfamethoxazole (TMP/SMX) (160/800 mg orally twice daily) after being diagnosed with brucellosis. Following defervescence and improvement in her general condition, fever recurred on the 12th day of treatment. A re-challenge drug test lead to causality assessment and treatment was switched to a combination of streptomycin (1 g intramuscularly) for 10 days and TMP/SMX (160/800 mg orally twice daily) for 4 weeks. Our patient is doing well after 12 months of follow-up.
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spelling pubmed-58072552018-02-13 Rifampicin-Induced Fever in a Patient with Brucellosis: A Case Report Yilmaz, Mesut Yasar, Canan Aydin, Selda Derin, Okan Ceylan, Bahadir Mert, Ali Drug Saf Case Rep Case Report We present a 35-year-old female patient who was started on rifampicin (900 mg orally once daily) and trimethoprim/sulfamethoxazole (TMP/SMX) (160/800 mg orally twice daily) after being diagnosed with brucellosis. Following defervescence and improvement in her general condition, fever recurred on the 12th day of treatment. A re-challenge drug test lead to causality assessment and treatment was switched to a combination of streptomycin (1 g intramuscularly) for 10 days and TMP/SMX (160/800 mg orally twice daily) for 4 weeks. Our patient is doing well after 12 months of follow-up. Springer International Publishing 2018-02-09 /pmc/articles/PMC5807255/ /pubmed/29427095 http://dx.doi.org/10.1007/s40800-018-0074-3 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Case Report
Yilmaz, Mesut
Yasar, Canan
Aydin, Selda
Derin, Okan
Ceylan, Bahadir
Mert, Ali
Rifampicin-Induced Fever in a Patient with Brucellosis: A Case Report
title Rifampicin-Induced Fever in a Patient with Brucellosis: A Case Report
title_full Rifampicin-Induced Fever in a Patient with Brucellosis: A Case Report
title_fullStr Rifampicin-Induced Fever in a Patient with Brucellosis: A Case Report
title_full_unstemmed Rifampicin-Induced Fever in a Patient with Brucellosis: A Case Report
title_short Rifampicin-Induced Fever in a Patient with Brucellosis: A Case Report
title_sort rifampicin-induced fever in a patient with brucellosis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807255/
https://www.ncbi.nlm.nih.gov/pubmed/29427095
http://dx.doi.org/10.1007/s40800-018-0074-3
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