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Quantitative analysis of receptor-mediated uptake and pro-apoptotic activity of mistletoe lectin-1 by high content imaging

Ribosome inactivating proteins (RIPs) are highly potent cytotoxins that have potential as anticancer therapeutics. Mistletoe lectin 1 (ML1) is a heterodimeric cytotoxic protein isolated from European Mistletoe and belongs to RIP class II. The aim of this project was to systematically study ML1 cell...

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Detalles Bibliográficos
Autores principales: Beztsinna, N., de Matos, M. B. C., Walther, J., Heyder, C., Hildebrandt, E., Leneweit, G., Mastrobattista, E., Kok, R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807326/
https://www.ncbi.nlm.nih.gov/pubmed/29426932
http://dx.doi.org/10.1038/s41598-018-20915-y