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Quantitative analysis of receptor-mediated uptake and pro-apoptotic activity of mistletoe lectin-1 by high content imaging
Ribosome inactivating proteins (RIPs) are highly potent cytotoxins that have potential as anticancer therapeutics. Mistletoe lectin 1 (ML1) is a heterodimeric cytotoxic protein isolated from European Mistletoe and belongs to RIP class II. The aim of this project was to systematically study ML1 cell...
Autores principales: | Beztsinna, N., de Matos, M. B. C., Walther, J., Heyder, C., Hildebrandt, E., Leneweit, G., Mastrobattista, E., Kok, R. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807326/ https://www.ncbi.nlm.nih.gov/pubmed/29426932 http://dx.doi.org/10.1038/s41598-018-20915-y |
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