Cargando…

Compositional marker in vivo reveals intramyocellular lipid turnover during fasting-induced lipolysis

Intramyocellular lipid (IMCL) is of particular metabolic interest, but despite many proton magnetic resonance spectroscopy ((1)H MRS) studies reporting IMCL content measured by the methylene (CH(2)) resonance signal, little is known about its composition. Here we validated IMCL CH(3):CH(2) ratio as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thankamony, Ajay, Kemp, Graham J., Koulman, Albert, Bokii, Vlada, Savage, David B., Boesch, Chris, Hodson, Leanne, Dunger, David B., Sleigh, Alison
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807358/ https://www.ncbi.nlm.nih.gov/pubmed/29426847 http://dx.doi.org/10.1038/s41598-018-21170-x

Ejemplares similares

Accumulation of saturated intramyocellular lipid is associated with insulin resistance
por: Savage, David B., et al.
Publicado: (2019)

Simple and effective exercise design for assessing in vivo mitochondrial function in clinical applications using (31)P magnetic resonance spectroscopy
por: Sleigh, Alison, et al.
Publicado: (2016)

The Effect of Aerobic Exercise on Intrahepatocellular and Intramyocellular Lipids in Healthy Subjects
por: Egger, Andrea, et al.
Publicado: (2013)

Intramyocellular lipid kinetics and insulin resistance
por: Guo, ZengKui
Publicado: (2007)

The effect of exercise on intramyocellular acetylcarnitine (AcCtn) concentration in adult growth hormone deficiency (GHD)
por: Meienberg, Fabian, et al.
Publicado: (2019)

Skeletal intramyocellular lipid metabolism and insulin resistance
por: Li, Yiran, et al.
Publicado: (2015)

Determinants of intramyocellular lipid accumulation in early childhood
por: Michael, Navin, et al.
Publicado: (2019)

Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans
por: Gemmink, Anne, et al.
Publicado: (2016)

Contribution of Intramyocellular Lipids to Decreased Computed Tomography Muscle Density With Age
por: Brennan, Nicholas A., et al.
Publicado: (2021)

Anogenital Distance from Birth to 2 Years: a Population Study
por: Thankamony, Ajay, et al.
Publicado: (2009)

Intramyocellular lipid droplets increase with progression of cachexia in cancer patients
por: Stephens, Nathan A., et al.
Publicado: (2011)

Intramyocellular lipids of muscle type in athletes of different sport disciplines
por: Nakagawa, Yoshinao, et al.
Publicado: (2017)

(31)P magnetization transfer measurements of P(i)→ATP flux in exercising human muscle
por: Sleigh, Alison, et al.
Publicado: (2016)

The development and validation of a fast and robust dried blood spot based lipid profiling method to study infant metabolism
por: Koulman, Albert, et al.
Publicado: (2014)

Reversal of intramyocellular lipid accumulation by lipophagy and a p62-mediated pathway
por: Lam, T, et al.
Publicado: (2016)

Intramyocellular lipid excess in the mitochondrial disorder MELAS: MRS determination at 7T
por: Golla, Sailaja, et al.
Publicado: (2017)

Higher Levels of IGF-I and Adrenal Androgens at Age 8 Years Are Associated with Earlier Age at Menarche in Girls
por: Thankamony, Ajay, et al.
Publicado: (2012)

Intramyocellular Triglyceride Content During the Early Course of Type 1 and Type 2 Diabetes
por: Schön, Martin, et al.
Publicado: (2023)

Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism
por: Morgan, Stuart A, et al.
Publicado: (2016)

Intramyocellular Ceramides: Subcellular Concentrations and Fractional De Novo Synthesis in Postabsorptive Humans
por: Chung, Jin Ook, et al.
Publicado: (2017)

Skeletal muscle and fiber type-specific intramyocellular lipid accumulation in obese mice
por: Umek, Nejc, et al.
Publicado: (2021)

Lipidomic Analyses, Breast- and Formula-Feeding, and Growth in Infants
por: Prentice, Philippa, et al.
Publicado: (2015)

Anogenital Distance and Penile Length in Infants with Hypospadias or Cryptorchidism: Comparison with Normative Data
por: Thankamony, Ajay, et al.
Publicado: (2013)

Tolvaptan use during hyperhydration in paediatric intracranial lymphoma with SIADH
por: Willemsen, Ruben H, et al.
Publicado: (2016)

Determinants of intramyocellular lipid accumulation after dietary fat loading in non‐obese men
por: Sakurai, Yuko, et al.
Publicado: (2011)

Intramyocellular triacylglycerol accumulation across weight loss strategies; Sub-study of the CENTRAL trial
por: Gepner, Yftach, et al.
Publicado: (2017)

Intramyocellular Lipids, Insulin Resistance, and Functional Performance in Patients with Severe Obstructive Sleep Apnea
por: Chien, Meng-Yueh, et al.
Publicado: (2020)

Noninvasive Assessment of Exercise-Related Intramyocellular Acetylcarnitine in Euglycemia and Hyperglycemia in Patients With Type 1 Diabetes Using (1)H Magnetic Resonance Spectroscopy: A randomized single-blind crossover study
por: Boss, Andreas, et al.
Publicado: (2011)

Abdominal fat depots associated with insulin resistance and metabolic syndrome risk factors in black African young adults
por: De Lucia Rolfe, Emanuella, et al.
Publicado: (2015)

Increased Fibro-Adipogenic Progenitors and Intramyocellular Lipid Accumulation in Obesity-Related Skeletal Muscle Dysfunction
por: Jia, Guanghong, et al.
Publicado: (2019)

Effect of electromyostimulation on intramyocellular lipids of the vastus lateralis in older adults: a randomized controlled trial
por: Hioki, Maya, et al.
Publicado: (2021)

Role of pulsatile growth hormone (GH) secretion in the regulation of lipolysis in fasting humans
por: Goldenberg, N., et al.
Publicado: (2022)

Effects of Dietary Protein and Fat Content on Intrahepatocellular and Intramyocellular Lipids during a 6-Day Hypercaloric, High Sucrose Diet: A Randomized Controlled Trial in Normal Weight Healthy Subjects
por: Surowska, Anna, et al.
Publicado: (2019)

Intramyocellular lipid accumulation after sprint interval and moderate‐intensity continuous training in healthy and diabetic subjects
por: Sjöros, Tanja, et al.
Publicado: (2019)

Timing of energy intake and the therapeutic potential of intermittent fasting and time-restricted eating in NAFLD
por: Marjot, Thomas, et al.
Publicado: (2023)

Serum Phthalate and Triclosan Levels Have Opposing Associations With Risk Factors for Gestational Diabetes Mellitus
por: Fisher, Benjamin G., et al.
Publicado: (2018)

Intermuscular Adipose Tissue Content and Intramyocellular Lipid Fatty Acid Saturation Are Associated with Glucose Homeostasis in Middle-Aged and Older Adults
por: Kim, Jung Eun, et al.
Publicado: (2017)

Intramyocellular Lipid Droplet Size Rather Than Total Lipid Content Is Related to Insulin Sensitivity After 8-Weeks of Overfeeding
por: Covington, Jeffrey D., et al.
Publicado: (2017)

Carbohydrate supplementation during prolonged cycling exercise spares muscle glycogen but does not affect intramyocellular lipid use
por: Stellingwerff, Trent, et al.
Publicado: (2007)

The impact of ageing, physical activity, and pre‐frailty on skeletal muscle phenotype, mitochondrial content, and intramyocellular lipids in men
por: St‐Jean‐Pelletier, Félix, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_9a4m8i1ho9q9mon8ets0vp4n6v