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Genome-wide tracking of dCas9-methyltransferase footprints
In normal mammalian development cytosine methylation is essential and is directed to specific regions of the genome. Despite notable advances through mapping its genome-wide distribution, studying the direct contribution of DNA methylation to gene and genome regulation has been limited by the lack o...
Autores principales: | Galonska, Christina, Charlton, Jocelyn, Mattei, Alexandra L., Donaghey, Julie, Clement, Kendell, Gu, Hongcang, Mohammad, Arman W., Stamenova, Elena K., Cacchiarelli, Davide, Klages, Sven, Timmermann, Bernd, Cantz, Tobias, Schöler, Hans R., Gnirke, Andreas, Ziller, Michael J., Meissner, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807365/ https://www.ncbi.nlm.nih.gov/pubmed/29426832 http://dx.doi.org/10.1038/s41467-017-02708-5 |
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