Altered Expression of Matrix Metalloproteinases and Their Endogenous Inhibitors in a Human Isogenic Stem Cell Model of Huntington's Disease

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by a progressive movement disorder, psychiatric symptoms, and cognitive impairments. HD is caused by a CAG repeat expansion encoding a stretch of polyglutamine residues in the N-terminus of mutant huntin...

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Detalles Bibliográficos
Autores principales: Naphade, Swati, Embusch, Alexander, Madushani, Kuruwitage Lakshika, Ring, Karen L., Ellerby, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807396/
https://www.ncbi.nlm.nih.gov/pubmed/29459817
http://dx.doi.org/10.3389/fnins.2017.00736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807396/
https://www.ncbi.nlm.nih.gov/pubmed/29459817
http://dx.doi.org/10.3389/fnins.2017.00736

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