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Altered Expression of Matrix Metalloproteinases and Their Endogenous Inhibitors in a Human Isogenic Stem Cell Model of Huntington's Disease

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by a progressive movement disorder, psychiatric symptoms, and cognitive impairments. HD is caused by a CAG repeat expansion encoding a stretch of polyglutamine residues in the N-terminus of mutant huntin...

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Detalles Bibliográficos
Autores principales:	Naphade, Swati, Embusch, Alexander, Madushani, Kuruwitage Lakshika, Ring, Karen L., Ellerby, Lisa M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807396/ https://www.ncbi.nlm.nih.gov/pubmed/29459817 http://dx.doi.org/10.3389/fnins.2017.00736

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