A cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed

Recent studies have reported intrinsic metabolic reprogramming in Pkd1 knock-out cells, implicating dysregulated cellular metabolism in the pathogenesis of polycystic kidney disease. However, the exact nature of the metabolic changes and their underlying cause remains controversial. We show herein t...

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Detalles Bibliográficos
Autores principales: Lin, Cheng-Chao, Kurashige, Mahiro, Liu, Yi, Terabayashi, Takeshi, Ishimoto, Yu, Wang, Tanchun, Choudhary, Vineet, Hobbs, Ryan, Liu, Li-Ka, Lee, Ping-Hsien, Outeda, Patricia, Zhou, Fang, Restifo, Nicholas P., Watnick, Terry, Kawano, Haruna, Horie, Shigeo, Prinz, William, Xu, Hong, Menezes, Luis F., Germino, Gregory G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807443/
https://www.ncbi.nlm.nih.gov/pubmed/29426897
http://dx.doi.org/10.1038/s41598-018-20856-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807443/
https://www.ncbi.nlm.nih.gov/pubmed/29426897
http://dx.doi.org/10.1038/s41598-018-20856-6

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