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A cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed
Recent studies have reported intrinsic metabolic reprogramming in Pkd1 knock-out cells, implicating dysregulated cellular metabolism in the pathogenesis of polycystic kidney disease. However, the exact nature of the metabolic changes and their underlying cause remains controversial. We show herein t...
Autores principales: | Lin, Cheng-Chao, Kurashige, Mahiro, Liu, Yi, Terabayashi, Takeshi, Ishimoto, Yu, Wang, Tanchun, Choudhary, Vineet, Hobbs, Ryan, Liu, Li-Ka, Lee, Ping-Hsien, Outeda, Patricia, Zhou, Fang, Restifo, Nicholas P., Watnick, Terry, Kawano, Haruna, Horie, Shigeo, Prinz, William, Xu, Hong, Menezes, Luis F., Germino, Gregory G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807443/ https://www.ncbi.nlm.nih.gov/pubmed/29426897 http://dx.doi.org/10.1038/s41598-018-20856-6 |
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