Next generation high throughput DNA damage detection platform for genotoxic compound screening

Methods for quantifying DNA damage, as well as repair of that damage, in a high-throughput format are lacking. Single cell gel electrophoresis (SCGE; comet assay) is a widely-used method due to its technical simplicity and sensitivity, but the standard comet assay has limitations in reproducibility...

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Detalles Bibliográficos
Autores principales: Sykora, Peter, Witt, Kristine L., Revanna, Pooja, Smith-Roe, Stephanie L., Dismukes, Jonathan, Lloyd, Donald G., Engelward, Bevin P., Sobol, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807538/
https://www.ncbi.nlm.nih.gov/pubmed/29426857
http://dx.doi.org/10.1038/s41598-018-20995-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807538/
https://www.ncbi.nlm.nih.gov/pubmed/29426857
http://dx.doi.org/10.1038/s41598-018-20995-w

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