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Next generation high throughput DNA damage detection platform for genotoxic compound screening
Methods for quantifying DNA damage, as well as repair of that damage, in a high-throughput format are lacking. Single cell gel electrophoresis (SCGE; comet assay) is a widely-used method due to its technical simplicity and sensitivity, but the standard comet assay has limitations in reproducibility...
Autores principales: | Sykora, Peter, Witt, Kristine L., Revanna, Pooja, Smith-Roe, Stephanie L., Dismukes, Jonathan, Lloyd, Donald G., Engelward, Bevin P., Sobol, Robert W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807538/ https://www.ncbi.nlm.nih.gov/pubmed/29426857 http://dx.doi.org/10.1038/s41598-018-20995-w |
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