The IAP family member BRUCE regulates autophagosome–lysosome fusion

Autophagy has an important role in cellular homeostasis by degrading and recycling cytotoxic components. Ubiquitination is known to target cargoes for autophagy; however, key components of this pathway remain elusive. Here we performed an RNAi screen to uncover ubiquitin modifiers that are required...

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Detalles Bibliográficos
Autores principales: Ebner, Petra, Poetsch, Isabella, Deszcz, Luiza, Hoffmann, Thomas, Zuber, Johannes, Ikeda, Fumiyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807552/
https://www.ncbi.nlm.nih.gov/pubmed/29426817
http://dx.doi.org/10.1038/s41467-018-02823-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807552/
https://www.ncbi.nlm.nih.gov/pubmed/29426817
http://dx.doi.org/10.1038/s41467-018-02823-x

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