Type I Interferon Signaling Is Required for CpG-Oligodesoxynucleotide-Induced Control of Leishmania major, but Not for Spontaneous Cure of Subcutaneous Primary or Secondary L. major Infection

We previously showed that in mice infected with Leishmania major type I interferons (IFNs) initiate the innate immune response to the parasite at day 1 and 2 of infection. Here, we investigated which type I IFN subtypes are expressed during the first 8 weeks of L. major infection and whether type I...

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Detalles Bibliográficos
Autores principales: Schleicher, Ulrike, Liese, Jan, Justies, Nicole, Mischke, Thomas, Haeberlein, Simone, Sebald, Heidi, Kalinke, Ulrich, Weiss, Siegfried, Bogdan, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807663/
https://www.ncbi.nlm.nih.gov/pubmed/29459858
http://dx.doi.org/10.3389/fimmu.2018.00079

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