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Preliminary study of automatic gastric cancer risk classification from photofluorography
AIM: To perform automatic gastric cancer risk classification using photofluorography for realizing effective mass screening as a preliminary study. METHODS: We used data for 2100 subjects including X-ray images, pepsinogen I and II levels, PGI/PGII ratio, Helicobacter pylori (H. pylori) antibody, H. p...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807881/ https://www.ncbi.nlm.nih.gov/pubmed/29467917 http://dx.doi.org/10.4251/wjgo.v10.i2.62 |
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author | Togo, Ren Ishihara, Kenta Mabe, Katsuhiro Oizumi, Harufumi Ogawa, Takahiro Kato, Mototsugu Sakamoto, Naoya Nakajima, Shigemi Asaka, Masahiro Haseyama, Miki |
author_facet | Togo, Ren Ishihara, Kenta Mabe, Katsuhiro Oizumi, Harufumi Ogawa, Takahiro Kato, Mototsugu Sakamoto, Naoya Nakajima, Shigemi Asaka, Masahiro Haseyama, Miki |
author_sort | Togo, Ren |
collection | PubMed |
description | AIM: To perform automatic gastric cancer risk classification using photofluorography for realizing effective mass screening as a preliminary study. METHODS: We used data for 2100 subjects including X-ray images, pepsinogen I and II levels, PGI/PGII ratio, Helicobacter pylori (H. pylori) antibody, H. pylori eradication history and interview sheets. We performed two-stage classification with our system. In the first stage, H. pylori infection status classification was performed, and H. pylori-infected subjects were automatically detected. In the second stage, we performed atrophic level classification to validate the effectiveness of our system. RESULTS: Sensitivity, specificity and Youden index (YI) of H. pylori infection status classification were 0.884, 0.895 and 0.779, respectively, in the first stage. In the second stage, sensitivity, specificity and YI of atrophic level classification for H. pylori-infected subjects were 0.777, 0.824 and 0.601, respectively. CONCLUSION: Although further improvements of the system are needed, experimental results indicated the effectiveness of machine learning techniques for estimation of gastric cancer risk. |
format | Online Article Text |
id | pubmed-5807881 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-58078812018-02-22 Preliminary study of automatic gastric cancer risk classification from photofluorography Togo, Ren Ishihara, Kenta Mabe, Katsuhiro Oizumi, Harufumi Ogawa, Takahiro Kato, Mototsugu Sakamoto, Naoya Nakajima, Shigemi Asaka, Masahiro Haseyama, Miki World J Gastrointest Oncol Retrospective Study AIM: To perform automatic gastric cancer risk classification using photofluorography for realizing effective mass screening as a preliminary study. METHODS: We used data for 2100 subjects including X-ray images, pepsinogen I and II levels, PGI/PGII ratio, Helicobacter pylori (H. pylori) antibody, H. pylori eradication history and interview sheets. We performed two-stage classification with our system. In the first stage, H. pylori infection status classification was performed, and H. pylori-infected subjects were automatically detected. In the second stage, we performed atrophic level classification to validate the effectiveness of our system. RESULTS: Sensitivity, specificity and Youden index (YI) of H. pylori infection status classification were 0.884, 0.895 and 0.779, respectively, in the first stage. In the second stage, sensitivity, specificity and YI of atrophic level classification for H. pylori-infected subjects were 0.777, 0.824 and 0.601, respectively. CONCLUSION: Although further improvements of the system are needed, experimental results indicated the effectiveness of machine learning techniques for estimation of gastric cancer risk. Baishideng Publishing Group Inc 2018-02-15 2018-02-15 /pmc/articles/PMC5807881/ /pubmed/29467917 http://dx.doi.org/10.4251/wjgo.v10.i2.62 Text en ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Retrospective Study Togo, Ren Ishihara, Kenta Mabe, Katsuhiro Oizumi, Harufumi Ogawa, Takahiro Kato, Mototsugu Sakamoto, Naoya Nakajima, Shigemi Asaka, Masahiro Haseyama, Miki Preliminary study of automatic gastric cancer risk classification from photofluorography |
title | Preliminary study of automatic gastric cancer risk classification from photofluorography |
title_full | Preliminary study of automatic gastric cancer risk classification from photofluorography |
title_fullStr | Preliminary study of automatic gastric cancer risk classification from photofluorography |
title_full_unstemmed | Preliminary study of automatic gastric cancer risk classification from photofluorography |
title_short | Preliminary study of automatic gastric cancer risk classification from photofluorography |
title_sort | preliminary study of automatic gastric cancer risk classification from photofluorography |
topic | Retrospective Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807881/ https://www.ncbi.nlm.nih.gov/pubmed/29467917 http://dx.doi.org/10.4251/wjgo.v10.i2.62 |
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