Involvement of MAF/SPP1 axis in the development of bone marrow fibrosis in PMF patients

Primary myelofibrosis (PMF) is a myeloproliferative neoplasm characterized by hyperplastic megakaryopoiesis and myelofibrosis. We recently described the upregulation of MAF (v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog) in PMF CD34+ hematopoietic progenitor cells (HPCs) compared to h...

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Detalles Bibliográficos
Autores principales: Ruberti, S, Bianchi, E, Guglielmelli, P, Rontauroli, S, Barbieri, G, Tavernari, L, Fanelli, T, Norfo, R, Pennucci, V, Fattori, G Corbizi, Mannarelli, C, Bartalucci, N, Mora, B, Elli, L, Avanzini, M A, Rossi, C, Salmoiraghi, S, Zini, R, Salati, S, Prudente, Z, Rosti, V, Passamonti, F, Rambaldi, A, Ferrari, S, Tagliafico, E, Vannucchi, A M, Manfredini, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808097/
https://www.ncbi.nlm.nih.gov/pubmed/28745329
http://dx.doi.org/10.1038/leu.2017.220

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