FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis

Mitochondrial dysregulation plays a central role in cancers and drives reactive oxygen species (ROS)-dependent tumor progression. We investigated the pro-tumoral roles of mitochondrial dynamics and altered intracellular ROS levels in pancreatic ductal adenocarcinoma (PDAC). We identified ‘family wit...

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Detalles Bibliográficos
Autores principales: Chattaragada, M S, Riganti, C, Sassoe, M, Principe, M, Santamorena, M M, Roux, C, Curcio, C, Evangelista, A, Allavena, P, Salvia, R, Rusev, B, Scarpa, A, Cappello, P, Novelli, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808099/
https://www.ncbi.nlm.nih.gov/pubmed/29059164
http://dx.doi.org/10.1038/onc.2017.358

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