Mitochondrial Proteins Coded by Human Tumor Viruses

Viruses must exploit the cellular biosynthetic machinery and evade cellular defense systems to complete their life cycles. Due to their crucial roles in cellular bioenergetics, apoptosis, innate immunity and redox balance, mitochondria are important functional targets of many viruses, including tumo...

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Autores principales: Cavallari, Ilaria, Scattolin, Gloria, Silic-Benussi, Micol, Raimondi, Vittoria, D'Agostino, Donna M., Ciminale, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808139/
https://www.ncbi.nlm.nih.gov/pubmed/29467726
http://dx.doi.org/10.3389/fmicb.2018.00081
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author Cavallari, Ilaria
Scattolin, Gloria
Silic-Benussi, Micol
Raimondi, Vittoria
D'Agostino, Donna M.
Ciminale, Vincenzo
author_facet Cavallari, Ilaria
Scattolin, Gloria
Silic-Benussi, Micol
Raimondi, Vittoria
D'Agostino, Donna M.
Ciminale, Vincenzo
author_sort Cavallari, Ilaria
collection PubMed
description Viruses must exploit the cellular biosynthetic machinery and evade cellular defense systems to complete their life cycles. Due to their crucial roles in cellular bioenergetics, apoptosis, innate immunity and redox balance, mitochondria are important functional targets of many viruses, including tumor viruses. The present review describes the interactions between mitochondria and proteins coded by the human tumor viruses human T-cell leukemia virus type 1, Epstein-Barr virus, Kaposi's sarcoma-associated herpesvirus, human hepatitis viruses B and C, and human papillomavirus, and highlights how these interactions contribute to viral replication, persistence and transformation.
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spelling pubmed-58081392018-02-21 Mitochondrial Proteins Coded by Human Tumor Viruses Cavallari, Ilaria Scattolin, Gloria Silic-Benussi, Micol Raimondi, Vittoria D'Agostino, Donna M. Ciminale, Vincenzo Front Microbiol Microbiology Viruses must exploit the cellular biosynthetic machinery and evade cellular defense systems to complete their life cycles. Due to their crucial roles in cellular bioenergetics, apoptosis, innate immunity and redox balance, mitochondria are important functional targets of many viruses, including tumor viruses. The present review describes the interactions between mitochondria and proteins coded by the human tumor viruses human T-cell leukemia virus type 1, Epstein-Barr virus, Kaposi's sarcoma-associated herpesvirus, human hepatitis viruses B and C, and human papillomavirus, and highlights how these interactions contribute to viral replication, persistence and transformation. Frontiers Media S.A. 2018-02-06 /pmc/articles/PMC5808139/ /pubmed/29467726 http://dx.doi.org/10.3389/fmicb.2018.00081 Text en Copyright © 2018 Cavallari, Scattolin, Silic-Benussi, Raimondi, D'Agostino and Ciminale. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Cavallari, Ilaria
Scattolin, Gloria
Silic-Benussi, Micol
Raimondi, Vittoria
D'Agostino, Donna M.
Ciminale, Vincenzo
Mitochondrial Proteins Coded by Human Tumor Viruses
title Mitochondrial Proteins Coded by Human Tumor Viruses
title_full Mitochondrial Proteins Coded by Human Tumor Viruses
title_fullStr Mitochondrial Proteins Coded by Human Tumor Viruses
title_full_unstemmed Mitochondrial Proteins Coded by Human Tumor Viruses
title_short Mitochondrial Proteins Coded by Human Tumor Viruses
title_sort mitochondrial proteins coded by human tumor viruses
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808139/
https://www.ncbi.nlm.nih.gov/pubmed/29467726
http://dx.doi.org/10.3389/fmicb.2018.00081
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