Phospho-Tau Bar Code: Analysis of Phosphoisotypes of Tau and Its Application to Tauopathy

Tau is a microtubule-associated protein which regulates the assembly and stability of microtubules in the axons of neurons. Tau is also a major component of neurofibrillary tangles (NFTs), a pathological hallmark in Alzheimer's disease (AD). A characteristic of AD tau is hyperphosphorylation wi...

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Detalles Bibliográficos
Autores principales: Kimura, Taeko, Sharma, Govinda, Ishiguro, Koichi, Hisanaga, Shin-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808175/
https://www.ncbi.nlm.nih.gov/pubmed/29467609
http://dx.doi.org/10.3389/fnins.2018.00044

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