CD137+CD154− Expression As a Regulatory T Cell (Treg)-Specific Activation Signature for Identification and Sorting of Stable Human Tregs from In Vitro Expansion Cultures

Regulatory T cells (Tregs) are an attractive therapeutic tool for several different immune pathologies. Therapeutic Treg application often requires prolonged in vitro culture to generate sufficient Treg numbers or to optimize their functionality, e.g., via genetic engineering of their antigen recept...

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Detalles Bibliográficos
Autores principales: Nowak, Anna, Lock, Dominik, Bacher, Petra, Hohnstein, Thordis, Vogt, Katrin, Gottfreund, Judith, Giehr, Pascal, Polansky, Julia K., Sawitzki, Birgit, Kaiser, Andrew, Walter, Jörn, Scheffold, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808295/
https://www.ncbi.nlm.nih.gov/pubmed/29467769
http://dx.doi.org/10.3389/fimmu.2018.00199

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