Identification of Casz1 as a Regulatory Protein Controlling T Helper Cell Differentiation, Inflammation, and Immunity

While T helper (Th) cells play a crucial role in host defense, an imbalance in Th effector subsets due to dysregulation in their differentiation and expansion contribute to inflammatory disorders. Here, we show that Casz1, whose function is previously unknown in CD4(+) T cells, coordinates Th differ...

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Detalles Bibliográficos
Autores principales: Bhaskaran, Natarajan, Liu, Zhihui, Saravanamuthu, Senthil S., Yan, Chunhua, Hu, Ying, Dong, Lijin, Zelenka, Peggy, Zheng, Lixin, Bletsos, Vassili, Harris, Rachel, Harrington, Brenna, Weinberg, Aaron, Thiele, Carol J., Ye, Fengchun, Pandiyan, Pushpa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808336/
https://www.ncbi.nlm.nih.gov/pubmed/29467767
http://dx.doi.org/10.3389/fimmu.2018.00184

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