Cargando…

Optimization and scale up of microfluidic nanolipomer production method for preclinical and potential clinical trials

BACKGROUND: The process of optimization and fabrication of nanoparticle synthesis for preclinical studies can be challenging and time consuming. Traditional small scale laboratory synthesis techniques suffer from batch to batch variability. Additionally, the parameters used in the original formulati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gdowski, Andrew, Johnson, Kaitlyn, Shah, Sunil, Gryczynski, Ignacy, Vishwanatha, Jamboor, Ranjan, Amalendu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808420/ https://www.ncbi.nlm.nih.gov/pubmed/29433518 http://dx.doi.org/10.1186/s12951-018-0339-0

Ejemplares similares

Current concepts in bone metastasis, contemporary therapeutic strategies and ongoing clinical trials
por: Gdowski, Andrew S., et al.
Publicado: (2017)

Development of Biodegradable Nanocarriers Loaded with a Monoclonal Antibody
por: Gdowski, Andrew, et al.
Publicado: (2015)

Bone-targeted cabazitaxel nanoparticles for metastatic prostate cancer skeletal lesions and pain
por: Gdowski, Andrew S, et al.
Publicado: (2017)

Scale up, optimization and stability analysis of Curcumin C3 complex-loaded nanoparticles for cancer therapy
por: Ranjan, Amalendu P, et al.
Publicado: (2012)

Novel Use of Hypoxia-Inducible Polymerizable Protein to Augment Chemotherapy for Pancreatic Cancer
por: Gdowski, Andrew, et al.
Publicado: (2022)

Mitigating prolonged QT interval in cancer nanodrug development for accelerated clinical translation
por: Ranjan, Amalendu P, et al.
Publicado: (2013)

Cabazitaxel-Loaded Nanoparticles Reduce the Invasiveness in Metastatic Prostate Cancer Cells: Beyond the Classical Taxane Function
por: Lampe, Jana B., et al.
Publicado: (2023)

MIEN1, a novel interactor of Annexin A2, promotes tumor cell migration by enhancing AnxA2 cell surface expression
por: Kpetemey, Marilyne, et al.
Publicado: (2015)

Prognostic impact of AnxA1 and AnxA2 gene expression in triple-negative breast cancer
por: Gibbs, Lee D., et al.
Publicado: (2017)

CRISPR deletion of MIEN1 in breast cancer cells
por: Van Treuren, Timothy, et al.
Publicado: (2018)

Role of Anti-Cancer Peptides as Immunomodulatory Agents: Potential and Design Strategy
por: Tripathi, Amit Kumar, et al.
Publicado: (2022)

Oncogenic activation in prostate cancer progression and metastasis: Molecular insights and future challenges
por: Dasgupta, Subhamoy, et al.
Publicado: (2012)

Antiangiogenic mechanisms and factors in breast cancer treatment
por: Castañeda-Gill, Jessica M., et al.
Publicado: (2016)

Perspectives in translating microfluidic devices from laboratory prototyping into scale-up production
por: Cong, Hengji, et al.
Publicado: (2022)

Absence of annexin I expression in B-cell non-Hodgkin's lymphomas and cell lines
por: Vishwanatha, Jamboor K, et al.
Publicado: (2004)

Effect of down-regulation of aquaporins in human corneal endothelial and epithelial cell lines
por: Shankardas, Jwalitha, et al.
Publicado: (2010)

Intersection of Smoking, Human immunodeficiency virus/acquired immunodeficiency syndrome and Cancer: Proceedings of the 8(th) Annual Texas Conference on Health Disparities
por: Rajendiran, Smrithi, et al.
Publicado: (2013)

Surface plasmon-assisted microscope
por: Borejdo, Julian, et al.
Publicado: (2018)

Single actomyosin motor interactions in skeletal muscle
por: Földes-Papp, Zeno, et al.
Publicado: (2011)

Breast cancer disparities: Frontline strategies, proceedings of the 7(th) annual texas conference on health disparities
por: Kpetemey, Marilyne, et al.
Publicado: (2012)

MIEN1 drives breast tumor cell migration by regulating cytoskeletal-focal adhesion dynamics
por: Kpetemey, Marilyne, et al.
Publicado: (2016)

Leading Predictors of COVID-19-Related Poor Mental Health in Adult Asian Indians: An Application of Extreme Gradient Boosting and Shapley Additive Explanations
por: Ikram, Mohammad, et al.
Publicado: (2022)

MyNRMN: A national mentoring and networking platform to enhance connectivity and diversity in the biomedical sciences
por: Ahmed, Toufeeq, et al.
Publicado: (2021)

Nuclear annexin II negatively regulates growth of LNCaP cells and substitution of ser 11 and 25 to glu prevents nucleo-cytoplasmic shuttling of annexin II
por: Liu, Jie, et al.
Publicado: (2003)

Long-Lived Bright Red Emitting Azaoxa-Triangulenium Fluorophores
por: Maliwal, Badri P., et al.
Publicado: (2013)

Casodex treatment induces hypoxia-related gene expression in the LNCaP prostate cancer progression model
por: Rothermund, Christy A, et al.
Publicado: (2005)

Lenticular mitoprotection. Part A: Monitoring mitochondrial depolarization with JC-1 and artifactual fluorescence by the glycogen synthase kinase-3β inhibitor, SB216763
por: Brooks, Morgan M., et al.
Publicado: (2013)

Evaluating Nanoparticles in Preclinical Research Using Microfluidic Systems
por: Zhu, Derui, et al.
Publicado: (2019)

Microfluidic Liver-on-a-Chip for Preclinical Drug Discovery
por: Fu, Jingyu, et al.
Publicado: (2023)

Preparation of Plasmonic Platforms of Silver Wires on Gold Mirrors and Their Application to Surface Enhanced Fluorescence
por: Shtoyko, Tanya, et al.
Publicado: (2014)

Reciprocal Regulation of Annexin A2 and EGFR with Her-2 in Her-2 Negative and Herceptin-Resistant Breast Cancer
por: Shetty, Praveenkumar K., et al.
Publicado: (2012)

Correction: Reciprocal Regulation of Annexin A2 and EGFR with Her-2 in Her-2 Negative and Herceptin-Resistant Breast Cancer
por: Shetty, Praveenkumar K., et al.
Publicado: (2012)

MIEN1 is tightly regulated by SINE Alu methylation in its promoter
por: Rajendiran, Smrithi, et al.
Publicado: (2016)

Overexpression of LLT1 (OCIL, CLEC2D) on prostate cancer cells inhibits NK cell-mediated killing through LLT1-NKRP1A (CD161) interaction
por: Mathew, Stephen O., et al.
Publicado: (2016)

Imaging viscosity of intragranular mucin matrix in cystic fibrosis cells
por: Requena, Sebastian, et al.
Publicado: (2017)

Optimization of lentiviral vector production for scale-up in fixed-bed bioreactor
por: Valkama, A J, et al.
Publicado: (2018)

Ovarian cancer: Current status and strategies for improving therapeutic outcomes
por: Chandra, Ashwin, et al.
Publicado: (2019)

Serum exosomal-annexin A2 is associated with African-American triple-negative breast cancer and promotes angiogenesis
por: Chaudhary, Pankaj, et al.
Publicado: (2020)

Correction to: Serum exosomal-annexin A2 is associated with African-American triple-negative breast cancer and promotes angiogenesis
por: Chaudhary, Pankaj, et al.
Publicado: (2020)

Community perspectives on AI/ML and health equity: AIM-AHEAD nationwide stakeholder listening sessions
por: Vishwanatha, Jamboor K., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_a7ab8cfj1b49aoes96ql73tn91