Cargando…

Trans-SNARE complex dynamics and number determine nascent fusion pore properties

The fusion pore is the first crucial intermediate formed during exocytosis, yet little is known regarding the mechanisms that determine the size and kinetic properties of these transient structures(1). Here, we reduced the number of available SNAREs in neurons and observed changes in transmitter rel...

Descripción completa

Detalles Bibliográficos
Autores principales: Bao, Huan, Das, Debasis, Courtney, Nicholas A., Jiang, Yihao, Briguglio, Joseph S., Lou, Xiaochu, Roston, Daniel, Cui, Qiang, Chanda, Baron, Chapman, Edwin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808578/
https://www.ncbi.nlm.nih.gov/pubmed/29420480
http://dx.doi.org/10.1038/nature25481