Differential Regulation of PAI-1 in Hantavirus Cardiopulmonary Syndrome and Hemorrhagic Fever With Renal Syndrome

We analyzed the levels of circulating tissue plasminogen activator (tPA) and plasminogen activator inhibitor (PAI)–1 in acute hantavirus cardiopulmonary syndrome (HCPS) and hemorrhagic fever with renal syndrome (HFRS). The levels of tPA commonly increased in both diseases, whereas PAI-1 correlated w...

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Autores principales: Bellomo, Carla, Korva, Miša, Papa, Anna, Mäkelä, Satu, Mustonen, Jukka, Avšič-Županc, Tatjana, Vaheri, Antti, Martinez, Valeria P, Strandin, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808793/
https://www.ncbi.nlm.nih.gov/pubmed/29450213
http://dx.doi.org/10.1093/ofid/ofy021
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author Bellomo, Carla
Korva, Miša
Papa, Anna
Mäkelä, Satu
Mustonen, Jukka
Avšič-Županc, Tatjana
Vaheri, Antti
Martinez, Valeria P
Strandin, Tomas
author_facet Bellomo, Carla
Korva, Miša
Papa, Anna
Mäkelä, Satu
Mustonen, Jukka
Avšič-Županc, Tatjana
Vaheri, Antti
Martinez, Valeria P
Strandin, Tomas
author_sort Bellomo, Carla
collection PubMed
description We analyzed the levels of circulating tissue plasminogen activator (tPA) and plasminogen activator inhibitor (PAI)–1 in acute hantavirus cardiopulmonary syndrome (HCPS) and hemorrhagic fever with renal syndrome (HFRS). The levels of tPA commonly increased in both diseases, whereas PAI-1 correlated with disease severity in HCPS but not in HFRS.
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spelling pubmed-58087932018-02-15 Differential Regulation of PAI-1 in Hantavirus Cardiopulmonary Syndrome and Hemorrhagic Fever With Renal Syndrome Bellomo, Carla Korva, Miša Papa, Anna Mäkelä, Satu Mustonen, Jukka Avšič-Županc, Tatjana Vaheri, Antti Martinez, Valeria P Strandin, Tomas Open Forum Infect Dis Brief Report We analyzed the levels of circulating tissue plasminogen activator (tPA) and plasminogen activator inhibitor (PAI)–1 in acute hantavirus cardiopulmonary syndrome (HCPS) and hemorrhagic fever with renal syndrome (HFRS). The levels of tPA commonly increased in both diseases, whereas PAI-1 correlated with disease severity in HCPS but not in HFRS. Oxford University Press 2018-01-17 /pmc/articles/PMC5808793/ /pubmed/29450213 http://dx.doi.org/10.1093/ofid/ofy021 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Bellomo, Carla
Korva, Miša
Papa, Anna
Mäkelä, Satu
Mustonen, Jukka
Avšič-Županc, Tatjana
Vaheri, Antti
Martinez, Valeria P
Strandin, Tomas
Differential Regulation of PAI-1 in Hantavirus Cardiopulmonary Syndrome and Hemorrhagic Fever With Renal Syndrome
title Differential Regulation of PAI-1 in Hantavirus Cardiopulmonary Syndrome and Hemorrhagic Fever With Renal Syndrome
title_full Differential Regulation of PAI-1 in Hantavirus Cardiopulmonary Syndrome and Hemorrhagic Fever With Renal Syndrome
title_fullStr Differential Regulation of PAI-1 in Hantavirus Cardiopulmonary Syndrome and Hemorrhagic Fever With Renal Syndrome
title_full_unstemmed Differential Regulation of PAI-1 in Hantavirus Cardiopulmonary Syndrome and Hemorrhagic Fever With Renal Syndrome
title_short Differential Regulation of PAI-1 in Hantavirus Cardiopulmonary Syndrome and Hemorrhagic Fever With Renal Syndrome
title_sort differential regulation of pai-1 in hantavirus cardiopulmonary syndrome and hemorrhagic fever with renal syndrome
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808793/
https://www.ncbi.nlm.nih.gov/pubmed/29450213
http://dx.doi.org/10.1093/ofid/ofy021
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