Antigen Presentation Profiling Reveals Recognition of Lymphoma Immunoglobulin Neoantigens

Cancer somatic mutations can generate neoantigens that distinguish malignant from normal cells (1–7). However, the personalized identification and validation of neoantigens remains a major challenge. Here we discover neoantigens in human mantle cell lymphomas using an integrated genomic and proteomi...

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Detalles Bibliográficos
Autores principales: Khodadoust, M.S., Olsson, N., Wagar, L.E., Haabeth, O.A.W., Chen, B., Swaminathan, K., Rawson, K., Liu, C.L., Steiner, D., Lund, P., Rao, S., Zhang, L., Marceau, C., Stehr, H., Newman, A.M., Czerwinski, D. K., Carlton, V.E.H., Moorhead, M., Faham, M., Kohrt, H.E., Carette, J., Green, M.R., Davis, M.M., Levy, R., Elias, J. E., Alizadeh, A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808925/
https://www.ncbi.nlm.nih.gov/pubmed/28329770
http://dx.doi.org/10.1038/nature21433

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