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Dynamic Basis for dG•dT misincorporation via tautomerization and ionization
Tautomeric and anionic Watson-Crick-like mismatches play important roles in replication and translation errors through mechanisms that are not fully understood. Using NMR relaxation dispersion, we resolved a sequence-dependent kinetic network connecting G•T/U wobbles with three distinct Watson-Crick...
Autores principales: | Kimsey, Isaac J., Szymanski, Eric S., Zahurancik, Walter J., Shakya, Anisha, Xue, Yi, Chu, Chia-Chieh, Sathyamoorthy, Bharathwaj, Suo, Zucai, Al-Hashimi, Hashim M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808992/ https://www.ncbi.nlm.nih.gov/pubmed/29420478 http://dx.doi.org/10.1038/nature25487 |
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