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A drift-diffusion checkpoint model predicts a highly variable and growth-factor-sensitive portion of the cell cycle G1 phase
Even among isogenic cells, the time to progress through the cell cycle, or the intermitotic time (IMT), is highly variable. This variability has been a topic of research for several decades and numerous mathematical models have been proposed to explain it. Previously, we developed a top-down, stocha...
Autores principales: | Jones, Zack W., Leander, Rachel, Quaranta, Vito, Harris, Leonard A., Tyson, Darren R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809023/ https://www.ncbi.nlm.nih.gov/pubmed/29432467 http://dx.doi.org/10.1371/journal.pone.0192087 |
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