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A drift-diffusion checkpoint model predicts a highly variable and growth-factor-sensitive portion of the cell cycle G1 phase

Even among isogenic cells, the time to progress through the cell cycle, or the intermitotic time (IMT), is highly variable. This variability has been a topic of research for several decades and numerous mathematical models have been proposed to explain it. Previously, we developed a top-down, stocha...

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Detalles Bibliográficos
Autores principales: Jones, Zack W., Leander, Rachel, Quaranta, Vito, Harris, Leonard A., Tyson, Darren R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809023/
https://www.ncbi.nlm.nih.gov/pubmed/29432467
http://dx.doi.org/10.1371/journal.pone.0192087

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