Characterization of Retinal Ganglion Cell and Optic Nerve Phenotypes Caused by Sustained Intracranial Pressure Elevation in Mice

Elevated intracranial pressure (ICP) can result in multiple neurologic sequelae including vision loss. Inducible models of ICP elevation are lacking in model organisms, which limits our understanding of the mechanism by which increased ICP impacts the visual system. We adapted a mouse model for the...

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Detalles Bibliográficos
Autores principales: Shen, Guofu, Link, Schuyler, Kumar, Sandeep, Nusbaum, Derek M., Tse, Dennis Y., Fu, Yingbin, Wu, Samuel M., Frankfort, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809383/
https://www.ncbi.nlm.nih.gov/pubmed/29434244
http://dx.doi.org/10.1038/s41598-018-21254-8

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