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Physician-initiated clinical study of limb ulcers treated with a functional peptide, SR-0379: from discovery to a randomized, double-blind, placebo-controlled trial

SR-0379 is a functional peptide that has wound healing effect with anti-microbial action, making it an ideal drug to prevent infection. To evaluate the safety, efficacy, and pharmacokinetics of SR-0379 for the treatment of leg ulcers, a physician-initiated, phase I/IIa, first-in-patient clinical stu...

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Detalles Bibliográficos
Autores principales: Nakagami, Hironori, Sugimoto, Ken, Ishikawa, Takahiro, Fujimoto, Taku, Yamaoka, Toshifumi, Hayashi, Misa, Kiyohara, Eiji, Ando, Hiroshi, Terabe, Yuta, Takami, Yoichi, Yamamoto, Koichi, Takeya, Yasushi, Takemoto, Minoru, Koshizaka, Masaya, Ebihara, Tamotsu, Nakamura, Ayumi, Nishikawa, Mitsunori, Yao, Xiang Jing, Hanaoka, Hideki, Katayama, Ichiro, Yokote, Koutaro, Rakugi, Hiromi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809414/
https://www.ncbi.nlm.nih.gov/pubmed/29449960
http://dx.doi.org/10.1038/s41514-018-0021-7