Induction of differentiation of intrahepatic cholangiocarcinoma cells to functional hepatocytes using an organoid culture system

Intrahepatic cholangiocarcinoma (IHCC) is a highly aggressive malignancy with a poor prognosis. It is thought to originate from cholangiocytes, which are the component cells of intrahepatic bile ducts. However, as patients with viral hepatitis often develop IHCC, it has been suggested that transform...

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Detalles Bibliográficos
Autores principales: Saito, Yoshimasa, Nakaoka, Toshiaki, Muramatsu, Toshihide, Ojima, Hidenori, Sukeda, Aoi, Sugiyama, Yuko, Uchida, Ryoei, Furukawa, Ryo, Kitahara, Aya, Sato, Toshiro, Kanai, Yae, Saito, Hidetsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809480/
https://www.ncbi.nlm.nih.gov/pubmed/29434290
http://dx.doi.org/10.1038/s41598-018-21121-6

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