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Intranasal Immunization with DnaK Protein Induces Protective Mucosal Immunity against Tuberculosis in CD4-Depleted Mice

Mycobacterium tuberculosis (Mtb) remains a global health challenge due to the limited efficacy of the Mtb vaccine in current use, Bacillus Calmette–Guérin (BCG). To date, there is no available vaccine for immunocompromised individuals. Thus, there is an urgent need to develop a new vaccine candidate...

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Detalles Bibliográficos
Autores principales:	Chuang, Yu-Min, Pinn, Michael L., Karakousis, Petros C., Hung, Chien-Fu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809501/ https://www.ncbi.nlm.nih.gov/pubmed/29473022 http://dx.doi.org/10.3389/fcimb.2018.00031

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