Resculpting the binding pocket of APC superfamily LeuT-fold amino acid transporters

Amino acid transporters are essential components of prokaryote and eukaryote cells, possess distinct physiological functions, and differ markedly in substrate specificity. Amino acid transporters can be both drug targets and drug transporters (bioavailability, targeting) with many monogenic disorder...

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Detalles Bibliográficos
Autores principales: Edwards, Noel, Anderson, Catriona M. H., Conlon, Nichola J., Watson, Andrew K., Hall, Rebecca J., Cheek, Timothy R., Embley, T. Martin, Thwaites, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809530/
https://www.ncbi.nlm.nih.gov/pubmed/29058016
http://dx.doi.org/10.1007/s00018-017-2677-8

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