Mammalian Adaptation of an Avian Influenza A Virus Involves Stepwise Changes in NS1

Influenza A viruses (IAVs) are common pathogens of birds that occasionally establish endemic infections in mammals. The processes and mechanisms that result in IAV mammalian adaptation are poorly understood. The viral nonstructural 1 (NS1) protein counteracts the interferon (IFN) response, a central...

Descripción completa

Detalles Bibliográficos
Autores principales: Chauché, C., Nogales, A., Zhu, H., Goldfarb, D., Ahmad Shanizza, A. I., Gu, Q., Parrish, C. R., Martínez-Sobrido, L., Marshall, J. F., Murcia, P. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809720/
https://www.ncbi.nlm.nih.gov/pubmed/29237841
http://dx.doi.org/10.1128/JVI.01875-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809720/
https://www.ncbi.nlm.nih.gov/pubmed/29237841
http://dx.doi.org/10.1128/JVI.01875-17

Ejemplares similares