Cargando…

Genetic determinants of sporadic breast cancer in Sri Lankan women

BACKGROUND: While a range of common genetic variants have been identified to be associated with risk of sporadic breast cancer in several Western studies, little is known about their role in South Asian populations. Our objective was to examine the association between common genetic variants in brea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sirisena, Nirmala Dushyanthi, Adeyemo, Adebowale, Kuruppu, Anchala I., Neththikumara, Nilaksha, Samaranayake, Nilakshi, Dissanayake, Vajira H. W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809862/ https://www.ncbi.nlm.nih.gov/pubmed/29433565 http://dx.doi.org/10.1186/s12885-018-4112-4

Ejemplares similares

Genetic Variants Associated with Clinicopathological Profiles in Sporadic Breast Cancer in Sri Lankan Women
por: Sirisena, Nirmala Dushyanthi, et al.
Publicado: (2018)

Genotype data for single nucleotide polymorphism markers in sporadic breast cancer related genes in a Sri Lankan case–control cohort of postmenopausal women
por: Sirisena, Nirmala Dushyanthi, et al.
Publicado: (2019)

Germline variants of uncertain significance, their frequency, and clinico-pathological features in a cohort of Sri Lankan patients with hereditary breast cancer
por: Gunawardena, Kawmadi, et al.
Publicado: (2023)

Implementation of genomic medicine in Sri Lanka: Initial experience and challenges
por: Sirisena, Nirmala D., et al.
Publicado: (2016)

Relative normalized luciferase activity for the recombinant vector constructs carrying the ancestral and variant alleles for XRCC2:rs3218550 and PHB:rs6917
por: Sirisena, Nirmala Dushyanthi, et al.
Publicado: (2018)

Breast cancer surveillance in BRCA positive Sri Lankan women: health equity for a high-risk group at a limited resource setting
por: Liyanage, Udari Apsara, et al.
Publicado: (2023)

Electrophoretic mobility shift assays implicate XRCC2:rs3218550C>T as a potential low-penetrant susceptibility allele for sporadic breast cancer
por: Sirisena, Nirmala D., et al.
Publicado: (2019)

Association of HLA class I and II genes with cutaneous leishmaniasis: a case control study from Sri Lanka and a systematic review
por: Samaranayake, Nilakshi, et al.
Publicado: (2016)

The Frequency and Spectrum of Chromosomal Translocations in a Cohort of Sri Lankans
por: Paththinige, Chamara S., et al.
Publicado: (2019)

Novel mutation in the SLC12A3 gene in a Sri Lankan family with Gitelman syndrome & coexistent diabetes: a case report
por: Subasinghe, Chandrika Jayakanthi, et al.
Publicado: (2017)

The first Sri Lankan family with Dent disease-1 due to a pathogenic variant in the CLCN5 gene: a case report
por: Ranawaka, Randula, et al.
Publicado: (2017)

A Case Series of Five Sri Lankan Patients with Ovotesticular Disorder of Sex Development
por: Wettasinghe, Kalum T., et al.
Publicado: (2012)

Genetics and genomic medicine in Sri Lanka
por: Sirisena, Nirmala D., et al.
Publicado: (2019)

Assessment of iron overload in a cohort of Sri Lankan patients with transfusion dependent beta thalassaemia and its correlation with pathogenic variants in HBB, HFE, SLC40A1, and TFR2 genes
por: Dissanayake, Ruwangi, et al.
Publicado: (2022)

Impact of Meditation-Based Lifestyle Practices on Mindfulness, Wellbeing, and Plasma Telomerase Levels: A Case-Control Study
por: Dasanayaka, Nirodhi Namika, et al.
Publicado: (2022)

Associations of meditation with telomere dynamics: a case–control study in healthy adults
por: Dasanayaka, Nirodhi Namika, et al.
Publicado: (2023)

The pattern of KRAS mutations in metastatic colorectal cancer: a retrospective audit from Sri Lanka
por: Sirisena, Nirmala Dushyanthi, et al.
Publicado: (2017)

Genetic diversity of variants involved in drug response and metabolism in Sri Lankan populations: implications for clinical implementation of pharmacogenomics
por: Chan, Sze Ling, et al.
Publicado: (2016)

A novel variant in the COL6A1 gene causing Ullrich congenital muscular dystrophy in a consanguineous family: a case report
por: Sirisena, Nirmala Dushyanthi, et al.
Publicado: (2021)

A Sri Lankan child with 49,XXXXY syndrome
por: Dissanayake, Vajira H. W., et al.
Publicado: (2010)

Functional evaluation of five BRCA2 unclassified variants identified in a Sri Lankan cohort with inherited cancer syndromes using a mouse embryonic stem cell-based assay
por: Sirisena, Nirmala, et al.
Publicado: (2020)

Design and implementation of a novel pharmacogenetic assay for the identification of the CYP2D6*10 genetic variant
por: Ranadeva, Nadeeka Dimuthu Kumari, et al.
Publicado: (2022)

Genetic variants in the cytochrome P450 2D6 gene in the Sri Lankan population
por: Tharanga, T. D. Praveen, et al.
Publicado: (2013)

Split hand/foot malformation with long bone deficiency associated with BHLHA9 gene duplication: a case report and review of literature
por: Paththinige, Chamara Sampath, et al.
Publicado: (2019)

Analyzing Safety Culture in Sri Lankan Industrial Chemical Laboratories
por: Samaranayake, Ashen I., et al.
Publicado: (2022)

The effects of meditation on length of telomeres in healthy individuals: a systematic review
por: Dasanayaka, Nirodhi N., et al.
Publicado: (2021)

Frequency of Hereditary Hemochromatosis Gene (HFE) Variants in Sri Lankan Transfusion-Dependent Beta-Thalassemia Patients and Their Association With the Serum Ferritin Level
por: Padeniya, Padmapani, et al.
Publicado: (2022)

Copy Number Variants Captured by the Array Comparative Genomic Hybridization in a Cohort of Patients Affected with Hereditary Colorectal Cancer in Sri Lanka: The First CNV Analysis Study of the Hereditary Colorectal Cancer in the Sri Lankan Population
por: Wijesiriwardhana, Prabhavi, et al.
Publicado: (2021)

Clinical Exome Gene Panel Analysis of a Cohort of Urothelial Bladder Cancer Patients from Sri Lanka
por: Malalasekera, Ajith P, et al.
Publicado: (2023)

Growth charts: do they reflect healthy growth in Sri Lankan children?
por: Wickramasinghe, V. P., et al.
Publicado: (2016)

Strategies for Genomic Medicine Education in Low- and Middle-Income Countries
por: Sirisena, Nirmala D., et al.
Publicado: (2019)

Elevated levels of whole blood nickel in a group of Sri Lankan women with endometriosis: a case control study
por: Silva, Nalinda, et al.
Publicado: (2013)

Profile of Hashimoto's Thyroiditis in Sri Lankans: Is There an Increased Risk of Ancillary Pathologies in Hashimoto's Thyroiditis?
por: Siriweera, Eranga Himalee, et al.
Publicado: (2010)

Free sugar intake and associated factors among Sri Lankan preschool children
por: Mututanthri, Shanika, et al.
Publicado: (2022)

Parathyroid hormone in Sri Lankan pregnant women: Vitamin D and other determinants
por: Kaneshapillai, Anusha, et al.
Publicado: (2021)

A novel mutation in SLC37A4 gene in a Sri Lankan boy with glycogen storage disease type Ib associated with very early onset neutropenia
por: Dissanayake, Vajira HW, et al.
Publicado: (2011)

Clinical and genetic features of Huntington disease in Sri Lanka
por: Sumathipala, Dulika S, et al.
Publicado: (2013)

Dyskeratosis congenita with a novel genetic variant in the DKC1 gene: a case report
por: Ratnasamy, Vithiya, et al.
Publicado: (2018)

Concomitant Guillain–Barré Syndrome in a young Sri Lankan male with severe ulcerative colitis
por: Jayasundara, Jayasundara Mudiyanselage Hishali Dahami, et al.
Publicado: (2022)

Persistence of antibody and T cell responses to the Sinopharm/BBIBP-CorV vaccine in Sri Lankan individuals
por: Jeewandara, Chandima, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_kvv932ht8pjj7o7rbhsr3o2o3g