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Characterization and validation of potential therapeutic targets based on the molecular signature of patient-derived xenografts in gastric cancer

BACKGROUND: Patient-derived xenograft (PDX) models with definite molecular signature are attractive preclinical models for development of novel targeted drugs. Here, we profiled and explored potential therapeutic targets based on characterized PDX models for advanced gastric cancer (AGC). METHODS: T...

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Detalles Bibliográficos
Autores principales:	Chen, Zuhua, Huang, Wenwen, Tian, Tiantian, Zang, Wanchun, Wang, Jingyuan, Liu, Zhentao, Li, Zhongwu, Lai, Yumei, Jiang, Zhi, Gao, Jing, Shen, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809945/ https://www.ncbi.nlm.nih.gov/pubmed/29433585 http://dx.doi.org/10.1186/s13045-018-0563-y

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