The chondroitin sulfate moiety mediates thrombomodulin-enhanced adhesion and migration of vascular smooth muscle cells

BACKGROUND: Thrombomodulin (TM), a transmembrane glycoprotein highly expressed in endothelial cells (ECs), is a potent anticoagulant maintaining circulation homeostasis. Under inflammatory states, TM expression is drastically reduced in ECs while vascular smooth muscle cells (VSMCs) show a robust ex...

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Detalles Bibliográficos
Autores principales: Pai, Vincent Chunpeng, Lo, I-Chung, Huang, Yan wun, Tsai, I-Ching, Cheng, Hui-Pin, Shi, Guey-Yueh, Wu, Hua-Lin, Jiang, Meei Jyh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809974/
https://www.ncbi.nlm.nih.gov/pubmed/29439742
http://dx.doi.org/10.1186/s12929-018-0415-7

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