SESOTHO trial (“Switch Either near Suppression Or THOusand”) – switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL: protocol of a multicenter, parallel-group, open-label, randomized clinical trial in Lesotho, Southern Africa

BACKGROUND: The World Health Organization (WHO) recommends viral load (VL) measurement as the preferred monitoring strategy for HIV-infected individuals on antiretroviral therapy (ART) in resource-limited settings. The new WHO guidelines 2016 continue to define virologic failure as two consecutive V...

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Detalles Bibliográficos
Autores principales: Amstutz, Alain, Nsakala, Bienvenu Lengo, Vanobberghen, Fiona, Muhairwe, Josephine, Glass, Tracy Renée, Achieng, Beatrice, Sepeka, Mamorena, Tlali, Katleho, Sao, Lebohang, Thin, Kyaw, Klimkait, Thomas, Battegay, Manuel, Labhardt, Niklaus Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810070/
https://www.ncbi.nlm.nih.gov/pubmed/29433430
http://dx.doi.org/10.1186/s12879-018-2979-y

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