Monitoring of argatroban and lepirudin anticoagulation in critically ill patients by conventional laboratory parameters and rotational thromboelastometry – a prospectively controlled randomized double-blind clinical trial

BACKGROUND: Argatroban or lepirudin anticoagulation therapy in patients with heparin induced thrombocytopenia (HIT) or HIT suspect is typically monitored using the activated partial thromboplastin time (aPTT). Although aPTT correlates well with plasma levels of argatroban and lepirudin in healthy vo...

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Detalles Bibliográficos
Autores principales: Beiderlinden, Martin, Werner, Patrick, Bahlmann, Astrid, Kemper, Johann, Brezina, Tobias, Schäfer, Maximilian, Görlinger, Klaus, Seidel, Holger, Kienbaum, Peter, Treschan, Tanja A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810183/
https://www.ncbi.nlm.nih.gov/pubmed/29426286
http://dx.doi.org/10.1186/s12871-018-0475-y

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