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Porphyromonas gingivalis lipopolysaccharide induces cognitive dysfunction, mediated by neuronal inflammation via activation of the TLR4 signaling pathway in C57BL/6 mice

BACKGROUND: Porphyromonas gingivalis lipopolysaccharide (P. gingivalis-LPS) is one of the major pathogenic factors of chronic periodontitis (CP). Few reports on the correlation between P. gingivalis-LPS and cognitive function exist. Thus, the present study aimed to investigate the effects of P. ging...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Yu, Chunbo, Zhang, Xuan, Chen, Huiwen, Dong, Jiachen, Lu, Weili, Song, Zhongchen, Zhou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810193/
https://www.ncbi.nlm.nih.gov/pubmed/29426327
http://dx.doi.org/10.1186/s12974-017-1052-x