Dexamethasone-induced production of reactive oxygen species promotes apoptosis via endoplasmic reticulum stress and autophagy in MC3T3-E1 cells

Apoptosis of osteoblasts, triggered by prolonged or excessive use of glucocorticoids (GCs), has been identified as a dominant contributor to the development of osteoporosis and osteonecrosis. However, the molecular mechanisms underlying GC-induced apoptosis are multifaceted and remain to be fully el...

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Detalles Bibliográficos
Autores principales: Liu, Wanlin, Zhao, Zhenqun, Na, Yuyan, Meng, Chenyang, Wang, Jianzhong, Bai, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810234/
https://www.ncbi.nlm.nih.gov/pubmed/29393368
http://dx.doi.org/10.3892/ijmm.2018.3412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810234/
https://www.ncbi.nlm.nih.gov/pubmed/29393368
http://dx.doi.org/10.3892/ijmm.2018.3412

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