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Fortunellin-Induced Modulation of Phosphatase and Tensin Homolog by MicroRNA-374a Decreases Inflammation and Maintains Intestinal Barrier Function in Colitis

Activation of phosphatase and tensin homolog (PTEN) is known to induce cell apoptosis. MicroRNA-374a (miR-374a), which can suppress PTEN expression, has been found abnormally expressed in inflammatory bowel disease (IBD). Fortunellin is a citrus flavonoid that is a potential anti-inflammation agent...

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Detalles Bibliográficos
Autores principales:	Xiong, Yongjian, Qiu, Juanjuan, Li, Changyi, Qiu, Yang, Guo, Li, Liu, Yuejian, Wan, Jiajia, Li, Yuchun, Wu, Guokai, Wang, Liang, Zhou, Zijuan, Dong, Jianyi, Du, Chunhua, Chen, Dapeng, Guo, Huishu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810275/ https://www.ncbi.nlm.nih.gov/pubmed/29472916 http://dx.doi.org/10.3389/fimmu.2018.00083

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